Our Chiefs vs Seahawks betting picks for NFL Week 7 2026 include odds analysis, best bets, key matchups and picks for your same-game parlay
One of the marquee matchups in NFL Week 7 is the Kansas City Chiefs vs. Seattle Seahawks Sunday night, at Lumen Field in Seattle.
Game time is 8:20 p.m. EST.
Both teams have legitimate Super Bowl ambitions. The Seahawks are coming off a Super Bowl win. For the Chiefs, the spotlight always falls on quarterback Patrick Mahomes and his ability to deliver in big games.
This time, Seattle faces the NFL’s leading rusher and former Seahawk, RB Kenneth Walker III (665 yards, 6 TDs), alongside Mahomes. Tomorrow night is a huge challenge for Mahomes, though. The Seahawks defence is No. 1 in the NFL (237.3 yards allowed per game) and can generate pressure and disrupt a QB’s offensive rhythm.
Can Seattle contain Mahomes? Or can the Chiefs consistently move the football against the Seahawks’ defence? And what teams can capitalize the most on red zone opportunities?
Key injuries: For the Chiefs, CB L’Jarius Sneed (knee) is questionable, while RB Brashard Smith (hamstring), OT Jaylon Moore (undisclosed), WR Rashee Rice (hamstring), OT Josh Simmons (lower back) and WR Tyquan Thornton are all out.
For the Seahawks, S Nick Emmanwori (hip), QB Drew Lock (elbow), LB Uchenna Nwosu (undisclosed), LP DeMarcus Lawrence (undisclosed), and LB Connor O’Toole (undisclosed) are all questionable. LB Chazz Surratt (calf), LB Drake Thomas (ankle), TE Elijah Arroyo (ankle), RB Zach Charbonnet (knee), RB Jadarian Price (undisclosed) are all out.
Key match for me is Mahomes versus Seattle’s pass rush. Mahomes remains one of the NFL’s most dangerous quarterbacks when plays break down.
Here are my Chiefs vs Seahawks picks.
Chiefs vs Seahawks Odds
In NFL picks at Betway, the Seahawks are -150 moneyline favourites, with the Chiefs +125. Seattle is favoured by 2.5 points (-125), while Kansas City is +2.5 points (+105). The total is set at 42.5, with the Over/Under at -110.
Oddsmakers are expecting a competitive, low-scoring game, with Seattle holding a slight edge. That’s a surprise to me, considering the Chiefs are 5-0, coming off a 22-5 shellacking of the L.A. Chargers. Chiefs +2.5 gives them some protection in a close finish.
Chiefs vs Seahawks Betting Picks
I’m going with Chiefs +2.5 (+105), since Kansas City has a strong scoring edge, a top-tier defence (second in points allowed per game, at 16.6), and a dominant ground game led by Walker. Plus, the championship pedigree in big games, led by Mahomes, TE Travis Kelce, and head coach Andy Reid.
The Walker revenge angle, returning to Seattle, overlaps with the Seahawks’ home-field advantage.
Seattle’s offence has struggled running the ball, and Charbonnet is out.
There’s also the not-so-small issue of Seahawks QB Sam Darnold’s interception problem; he’s now up to seven for the season.
I’m taking the Over. Both offences average solid point totals, and the difference-maker for me is the explosive potential of Walker, Mahomes, and Seattle’s WR Jaxon Smith-Njigba.
Speaking of Smith-Njigba, if I’m committing to the over, that means a productive game for the receiver, so let’s go over 90+ receiving yards at in NFL betting Betway (-125).
JSN leads the NFL in receptions (49) and receiving yards (717 in six games, so 119.5 YPG). Plus, he leads the NFL in receiving TDs with seven. Seattle’s lack of a run game could force more attention his way.
Chiefs vs Seahawks Same Game Parlay
If you’re looking at parlay options for tomorrow night, why not Chiefs +2.5, Walker 60+ rushing yards, and Mahomes 200+ passing yards, for a +240 total?
