Visit the Betway online sportsbook for the latest NFL odds and lines, and Betway’s NFL picks page for picks and predictions throughout the season.

NEW YORK JETS (+7.5) @ Green Bay Packers 

The Jets are coming off a 40-17 divisional win over the Miami Dolphins last Sunday, and yet find themselves big underdogs on the road in Green Bay this week.

The Packers have been one of the best teams in the NFL for years and are led by four-time MVP Aaron Rodgers at quarterback, which explains why they’re favourites on Sunday. They simply haven’t been at their best so far this season, though, and lost 27-22 to the New York Giants last weekend in London.

Green Bay rank 22nd in the NFL in points per game and their defence struggled to get off the field against the Giants, allowing 125 yards on the ground and three rushing touchdowns. They could face similar problems against the Jets’ ground game, with rookie Breece Hall looking like a star after a 197-yard performance last week.

The Jets have some great, young offensive weapons, and second-year quarterback Zach Wilson is back after missing the first three games of the year through injury. He calmly led the Jets to a really impressive win last week, and that performance suggests they’re capable of staying within a touchdown against the out-of-sorts Packers.

MINNESOTA VIKINGS (-3.5) @ Miami Dolphins 

The Vikings have won three in a row to move to 4-1 for the season, and they’re now a game clear at the top of the NFC North.

Minnesota’s offense is clicking, having scored at least 28 points in three straight games, and they should keep that streak going against a Miami defence that has allowed the fourth-most points per game of any team.

The Dolphins are reeling after giving up 40 to the Jets, and their top two quarterbacks are both currently in concussion protocol. Backup Teddy Bridgewater has a chance of returning on Sunday, but if he doesn’t recover in time it’ll be third-stringer Skylar Thompson under centre for the second consecutive game.

Whether it’s Bridgewater or Thompson, Miami’s defensive struggles will be hard to overcome and Minnesota should ease to victory.

NEW YORK GIANTS (+5.5) vs Baltimore Ravens 

The Giants have been arguably the biggest surprise in the NFL this season. They’re 4-1 thanks to last week’s upset win over the Packers in London, and look to have a real shot at the playoffs.

New head coach Brian Daboll has built an offense that controls the ball and minimises quarterback Daniel Jones’ weaknesses. Star running back Saquon Barkley is back to his explosive best, and the Giants rank second in the NFL in rushing yards per game so far.

They now face a tough test against the Ravens, who are 3-2 but haven’t been as explosive offensively this season after Marquise Brown left in free agency. Starting wide receiver Rashod Bateman is also currently not practicing with a foot injury, so Baltimore could struggle to move the ball through the air against a Giants defence that has allowed just 18.6 points per game this season.

In what should be a low-scoring game in which both teams look to run the ball, it’s well worth backing the Giants to at least keep the score close, and possibly even move to 5-1.

KANSAS CITY CHIEFS (+2.5) vs Buffalo Bills 

This is clearly the game of the week, as the current top two favourites in the Super Bowl betting meet at Arrowhead Stadium, both looking to move to 5-1 and go clear at the top of the AFC.

This is just the second time since 2019 that the Chiefs have been underdogs at home. Kansas City have won eight consecutive games at Arrowhead dating back to last season, but the Bills have been so impressive this season that they’re favoured by just under a field goal on Sunday.

The Chiefs look like the team to back, though. They have a formidable record as underdogs with Patrick Mahomes at quarterback, having not only gone 4-1 against the spread in their last five games as underdogs, but also 4-1 outright.

They beat the Bills 42-36 in overtime in an incredible Divisional Round playoff game last January, and although the loss of Tyreek Hill in the offseason has made the offense slightly less potent, the atmosphere at Arrowhead should give the Chiefs enough of an edge to win this game.

These are two elite quarterbacks at the peak of their powers, but Patrick Mahomes has come out on top in so many huge games that he’s worth trusting to win this duel with Josh Allen.