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NFL betting tips: 4 picks against the spread for Week 5 2022

07 Oct | BY Guy Giles | MIN READ TIME |
NFL betting tips: 4 picks against the spread for Week 5 2022

Guy Giles makes his NFL betting picks for Week 5 of the 2022 season, with four bets against the spread.

Visit the Betway online sportsbook for the latest NFL odds and lines, and Betway’s NFL picks page for picks and predictions throughout the season.

LOS ANGELES CHARGERS (-2.5) vs Cleveland Browns {ODDS:1012773992:10/11}

The Chargers bounced back from their shock 28-point defeat by the Jaguars at home in Week 3 with a 34-24 win in Houston last weekend.

Los Angeles is now 2-2 on the season, good enough for second in the AFC West, widely considered the toughest division in the NFL this year.

While the Texans didn’t pose the biggest threat and that Week 4 victory doesn’t prove much, things are trending in the right direction for the Chargers.

Quarterback Justin Herbert looked to be on the mend from his rib injury, throwing for 340 yards and two touchdowns, while running back Austin Ekeler got off the mark for the season as he found his way into the endzone three times.

The Browns are also at 2-2 on the season and sit joint-top of the AFC North, but are coming off a disappointing 23-20 defeat by the Atlanta Falcons.

Stand-in signal caller Jacoby Brissett showed his limitations in that game, managing just 234 yards for no touchdowns and an interception.

The Browns cannot depend on their one-two punch running back duo of Nick Chubb and Kareem Hunt to win them every game, particularly when they come up against a competent defensive unit like the Chargers.

Having lost to the Falcons and the New York Jets already this season, the Browns are likely to struggle against a true playoff contender in the Chargers.

DETROIT LIONS (+3.5) vs New England Patriots {ODDS:1012781105:20/23}

The Detroit Lions are the most exciting team in the NFL so far this season, and the stats prove it.

Dan Campbell’s team have scored 140 points in four games at an average of 35 per game, and are gaining more offensive yards than any other team in the league at 436.8 per contest.

On the other side of the ball, Detroit has conceded 141 points, also the highest tally in the league, while giving up another league-high 444.8 offensive yards per game.

The Lions are unlucky to be 1-3, having lost close games to the undefeated Philadelphia Eagles, the Minnesota Vikings and the Seattle Seahawks, with all three losses coming by a field goal or less.

Although they are dealing with injuries to receivers Amon Ra St-Brown and DJ Chark, and star running back D’Andre Swift, the Lions have a great chance of notching their second win of the season against a depleted Patriots team.

New England quarterback Mac Jones is struggling with an ankle injury, while back up Brian Hoyer is out with a concussion. Jones returned to limited practice in midweek, but it would be a surprise if he suits up on Sunday. That puts third-string Bailey Zappe in line for his first career start, with top receiver Jakobi Meyers also a potential absence with a knee problem.

Take the Lions and the points in this one.

TENNESSEE TITANS (-1.5) vs Washington Commanders {ODDS:1012772511:20/23}

After going 0-2 to start the season, including a loss at home to the New York Giants on opening weekend, the Titans are starting to look like themselves again.

Back-to-back wins over playoff hopefuls Las Vegas and Indianapolis mean Tennessee heads to Washington with plenty of momentum.

Derrick Henry has scored a touchdown in three consecutive games, while Ryan Tannehill is coming off a 17-for-21 performance with two touchdowns and no picks.

The only concern for Tennessee is their receiving corps, with rookie Treylon Burks set to miss a few weeks through injury, leaving Robert Woods as their No.1 wideout alongside Nick Westbook-Ikhine, Cody Hollister and Kyle Philips.

They should still have enough firepower to beat a Washington team that is 1-3 and has looked pretty dire in the opening weeks of the season.

The Commanders have put up just 73 points on offense, the joint-sixth worst tally in the league, and have 107 points against, the fourth-worst defensive record in the NFL.

Quarterback Carson Wentz has put up eight passing touchdowns but has mixed in five interceptions while being sacked a league-high 17 times.

Tennessee is simply a better team than Washington, and should be able to cover this spread pretty comfortably on Sunday.

PHILADELPHIA EAGLES (-4.5) vs Arizona Cardinals {ODDS:1012775498:20/23}

The Eagles are the only remaining undefeated team in the NFL, and have looked mightily impressive in going 4-0 to this point.

Following a tight three-point win over the Lions in Week 1, Philadelphia has beaten Minnesota by 17 points, Washington by 16 and Jacksonville by eight.

Jalen Hurts is playing at an MVP level at quarterback, passing for 1,120 yards and four touchdowns while rushing for 205 yards and another four scores, and the defense is ranking in the top three for yards against and has effected a league-high 10 takeaways.

The only criticism you could level at the Eagles at this point is that their opponents haven’t been the toughest, and Arizona are undoubtedly their biggest test yet.

The Cardinals have not been playing particularly well, though, with their 2-2 record papering over the cracks of some concerning performances.

Kyler Murray has been carrying them on offense, with the Arizona receiving unit beset by injuries and James Conner having just a single touchdown from the backfield.

Both of Arizona’s losses this season have come against playoff teams in the Rams and the Chiefs, and both came by a comfortable margin, including an eight-point defeat by LA in Glendale.

The Eagles should be heading back to Philadelphia at 5-0, and their momentum on both sides of the ball should see them cover the spread in this one.

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Guy Giles

Guy Giles

Sports writer who produces regular football and cricket tips, while also covering a range of other sports.

Guy Giles

Guy Giles

Sports writer who produces regular football and cricket tips, while also covering a range of other sports.