Visit Betway’s NFL picks page for picks and predictions throughout the season.

KANSAS CITY CHIEFS (-5.5) vs Indianapolis Colts

The Chiefs are once again looking like formidable Super Bowl contenders this season. They blew out the Arizona Cardinals 44-21 in Week 1 before overcoming the Los Angeles Chargers in an AFC West showdown last Thursday.

Kansas City’s offense has been just as prolific as last season despite trading away star receiver Tyreek Hill over the summer, as MVP Patrick Mahomes has passed for 595 yards, seven touchdowns and no interceptions so far.

The Chiefs now take on the Colts, who were stunned 24-0 by the Jacksonville Jaguars last Sunday. Indianapolis are now 0-1-1, having tied with the Houston Texans in Week 1.

With two disappointing results against teams expected to be poor this season, it’s been a really bad start for the Colts, and it doesn’t get any easier here. Along with the Buffalo Bills, the Chiefs have looked like the class of the AFC this year and should comfortably cover the spread on the road.

NEW YORK JETS (+6.5) vs Cincinnati Bengals

After losing to the Baltimore Ravens in Week 1, the Jets moved to 1-1 for the season last week by beating the Cleveland Cavaliers 31-30.

Rookies Garrett Wilson and Breece Hall scored three touchdowns combined for a Jets offense that now looks stacked with exciting young weapons.

The Bengals, meanwhile, have made a terrible start after reaching the Super Bowl last year, losing to the Pittsburgh Steelers and Dallas Cowboys. It’s hard to see why they’re favoured by almost a touchdown on the road here.

Quarterback Joe Burrow has thrown for more interceptions (4) than touchdowns (3) so far, and has lost games to Mitchell Trubisky and Cooper Rush. The Bengals’ offensive line has struggled to protect Burrow, and unless that unit shows massive improvement in Week 3 the Jets should be able to cover at home.

JACKSONVILLE JAGUARS (+7.5) vs Los Angeles Chargers

The Jaguars caused a huge upset against the Colts last week, having come into the game as three-point underdogs.

Quarterback Trevor Lawrence was outstanding, completing 25 of 30 passes for 235 yards, two touchdowns and no interceptions, while the defence held Indianapolis’ star running back Jonathan Taylor to just 54 yards and forced three interceptions from Matt Ryan.

The Jags face a tougher test against the Chargers, who lost 27-24 to the Chiefs last Sunday to drop to 1-1 for the season.

The Chargers remain strong contenders in the AFC despite that defeat, but star quarterback Justin Herbert is dealing with a rib injury he suffered last weekend, and the Jaguars should be able to keep this game within a touchdown if Herbert is limited.

TAMPA BAY BUCCANEERS (-1.5) vs Green Bay Packers

The Buccaneers earned a big win on the road against the New Orleans Saints last week, scoring 17 points in the fourth quarter to beat their divisional rivals 20-10.

Tampa Bay are dealing with several problems offensively, with receivers Chris Godwin, Russell Gage and Julio Jones all injured and Mike Evans suspended for Sunday’s game, while running back Leonard Fournette is also banged up. They’re 2-0 nonetheless, despite having played both games on the road so far.

The Buccaneers’ defence has allowed just 13 points across two games so far, and should pose big problems for Aaron Rodgers and the Green Bay offense. The Packers were beaten 23-7 on the road by the Minnesota Vikings in Week 1 before bouncing back with a win over the Chicago Bears last week.

Rodgers hasn’t looked his best this season after losing star receiver Davante Adams over the summer, and with No. 1 receiver Allen Lazard dealing with an ankle injury, it’s going to be tough for Green Bay to put up points against this Buccaneers unit.