8/13 - Tomas Berdych to beat Nick Kyrgios

Australian hopes of a winner Down Under are likely to be squashed on Friday when Nick Kyrgios takes on Tomas Berdych.

The big Czech has progressed past the third round in nine of the last 11 grand slams and, in his last five visits to the Australian Open, he has reached two semi-finals and three quarter-finals.

Kyrgios has had limited success against top 10 players - winning just 28 per cent of his encounters - and Berdych’s experience should see him through.

1/9 - Roger Federer to beat Grigor Dimitrov

Once nicknamed 'baby Fed', Grigor Dimitrov has got nowhere near to emulating the great Roger Federer.

Federer has won all four meetings with the Bulgarian, dropping just one set in the process.

The 17-time major winner was at his best on Tuesday, serving 25 aces in a straight-sets win against Alexandr Dolgopolov -  and a similar outcome is to be expected here.

7-5 - David Goffin to beat Dominic Thiem

David Goffin’s odds to beat Dominic Thiem - who he is ranked four places above - are surprising.

Goffin enjoyed a career-best season last year, reaching the finals of Gstaad, Hertogenbosch and, while representing Belgium - the Davis Cup.

Despite having plenty of promise, the 22-year-old Thiem has only progressed past the third round of a slam once in his career, while Goffin leads their head-to-head 4-2.

4/11 - Marin Cilic to beat Roberto Bautista Agut

Marin Cilic will have no problems seeing off an exhausted Roberto Bautista Agut and to reach the Australian Open fourth round for the fourth time in his career.

As if going all the way in Auckland last week wasn’t enough for Agut, he has endured back-to-back five setters to reach the third round in Melbourne.

The tenacious Spaniard has lost both his previous encounters with Cilic and has little hope on Friday.

1/10 - Jo-Wilfried Tsonga to beat Pierre-Hughes Herbert

The contest between Jo-Wilfriend Tsonga and Pierre-Hughes Herbert should be entertaining.

It is Tsonga, though, who will trumph over his fellow Frenchman.

The 30-year-old is the superior player and will not be troubled by a player who had previously lost four of his five matches at majors.

A £10 bet on the five-fold accumulator returns £64.61*.

Australian Open betting

*Odds and amounts correct at the time of publication but subject to change. See site for latest.