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Frankfurt to beat Inter Milan (17:55)

Frankfurt are currently on a nine-match unbeaten run in all competitions and have their last three.

The German side beat Shakhtar 4-1 at the Commerzbank Arena in the previous round and have a 100 per cent home record in the Europa League this season, having also dispatched Lazio and Marseille in the group stage.

Inter lost 2-1 away to Serie A strugglers Cagliari and have won just three of their last 11 away games in all competitions.

Sevilla to beat Slavia Prague (17:55)

Sevilla come into this with a 100 per cent record at home in their five Europa League games this season.

Los Rojiblancos have won 13 and lost just two of their last 17 matches in all competitions at the Ramon Sanchez Pizjuan.

They can be trusted to beat a Slavia Prague side who lost two away games out of three in the group stage.

Arsenal to beat Stade Rennes (17:55)

Stade Rennes’ 2-0 win over second-tier Orleans in the Coupe de France last weekend was only their second victory in their last five matches in all competitions.

The French side blew a two-goal lead at home to Betis, who are mid-table in La Liga, in the first leg of their round-of-32 tie to draw 3-3.

The visit of Arsenal represents their toughest Europa League test so far. And given Unai Emery’s side have won six of their eight games in the competition and are unbeaten in four, they should be backed at even money.

Zenit to beat Villarreal (17:55)

Zenit beat Fenerbahce 3-1 last time out at the Krestovsky Stadium in the second leg of the previous knock-out round.

The Russian side have won 12 of their 14 home games in all competitions this season, including five from five in Europe.

They should easily beat Villarreal, who have won just one of their last 14 away games in all competitions and, sitting third-bottom in La Liga, could prioritise safety.

Napoli to beat RB Salzburg (20:00)

Napoli’s 2-1 defeat at home to Serie A leaders Juventus last weekend was their first at the San Paolo this season in all competitions.

The Partonopei have only failed to win five of their 19 home games so far and took seven points from games against Liverpool, Paris Saint-Germain and Red Star in the Champions League.

Salzburg were beaten 2-0 at Rapid Vienna in the Austrian Bundesliga last time out on the road and have lost two of their last three away games in all competitions – their worst run of the season.

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